Outcome of Antenatally Presenting Posterior Urethral Valves (PUV) in Children.

BACKGROUND To analyze the outcome of children with posterior urethral valves who presented with antenatal hydronephrosis. METHODS A 10-year retrospective review of records of 70 children with posterior urethral valves. RESULTS The mean (SD) gestational age at diagnosis was 34 (4.48) weeks, and age at intervention was 130.5 (170.9) days. The nadir creatinine was significantly raised (<1.2 mg/dl) in children with oligohydramnios and diversion. CONCLUSION All boys with antenatally detected hydronephrosis need postnatal evaluation to rule out posterior urethral valves. Short term outcome is improved with postnatal treatments, and longer follow-up is needed to ensure a favourable outcome.